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  • Writer's pictureSuzie

The Estrobolome - why is gut health so important in menopause?

Gut Health, microbiome support, healthy hear about it all the time, and figure you should eat healthier meals and include more gut friendly nutrients to support your gut system. But do you really know why this is especially important in menopause, let alone for overall health?

Knowledge about how the gut-microbiome alters aspects of our immune, metabolic and nervous system health has increased massively over the past decade, and thankfully for those of us in the throes of menopause, some of this knowledge has also shed some light on why we experience certain symptoms during the hormonal transition.

For women going through menopause, the decline in oestrogen levels impacts on our gut health.

There is an entire world inside our guts: it’s called the gut microbiome, and it contains TRILLIONS of bacteria. Alongside our skin, the gut microbiome is one of the largest organs in the body and each person's microbiome is as unique as their own fingerprints. It's also incredibly powerful because it contains more microbes than we each have cells in our bodies! Most of these microbes reside in the gastrointestinal tract and help to:

  • break down foods

  • supply the gut with energy

  • make vitamins

  • break down toxins

  • protect against pathogens

We all know about gut instinct, butterflies in the stomach and how terror turns our tummies to liquid, but now there's emerging evidence of the gut microbiome being involved in disorders such as depression, anxiety and overall mental health. We always thought there was a gut-brain axis but couldn't quite figure out why. However, there is a powerful connection between your gut and your brain (which is why we get a 'gut feeling' and the gut is referenced as our ‘second brain’), therefore many symptoms that you may be experiencing in menopause, such as brain fog, depression, anxiety and mood swings can be indicative of the health of your gut microbiome.

There are about 60 different organisms affecting our oestrogen production and our feminine health. This group of fungi and bacteria is called the estrobolome! I know! Just as we got our heads around 'gut microbiome' - there's an estrobolome to take into consideration and it is slowly becoming the Holy Grail of researchers looking for ways to make menopause more bearable for women.

So, if we focus on improving our gut health, imagine what happens to our hot flushes, energy levels, sleep, brain function and moods! This immense community of bacteria regulates the production of oestrogen, the main female hormone, which drops drastically during menopause. This has an overarching impact on our health, contributing to the symptoms listed above, as well as dozens of other issues making many women feel miserable during menopause.

So what exactly is an Estrobolome?

The estrobolome is a biome within the gut microbiome, which regulates how our body processes oestrogen. This process occurs by oestrogen-metabolising enzymes called beta-glucuronidases, which convert oestrogens into their active forms so that they can enter the blood circulation and reach other tissues in the body. When the gut microbiome is healthy, the estrobolome produces just the right amount of beta-glucuronidase to keep oestrogen in balance.

However, when there is gut dysbiosis (i.e. bacterial imbalances), the beta-glucuronidase can increase, resulting in less oestrogen being excreted out of the body so that more remains within the body to be recirculated, bind to receptors, and impact on various physiologic processes, in effect reversing the normal detoxification process. Oestrogen plays many vital roles in the human body. It regulates body fat deposition, energy balance, female reproductive function, cardiovascular health, bone turnover, and cell replication. Gut dysbiosis has the potential to alter the estrobolome, disrupt oestrogen homeostasis, and impair these processes, leading to inflammation and if we're not careful, more serious chronic illnesses later on.

On a positive note..whilst our hormones are acting out of control, we can at least control the ability to improve our gut health! Small changes to diet, lifestyle and exercise regimes can make huge improvements to your gut health. A healthy and varied diet is, of course, very important, but it may not be enough to keep up the diversity of the estrobolome. This is why probiotics can be so beneficial.

Many of us have seen probiotics on the supermarket shelves. But what exactly are they and do they work?

Probiotics, the most common of which are strains of Lactobacillus and Bifidobacterium, are live organisms. The idea is that, after you’ve swallowed them, they’ll make their way through the stomach and take up residence in your gut. Certain strains have been proven to be effective against loss of bone mass, to prevent depression, or to decrease the chances of insulin resistance and diabetes. Others can help with weight management and a host of other menopause-related problems.

But just any probiotic won’t do. It’s important that you select a product that has been formulated specifically for the needs of the menopausal woman. Many women also want their supplements to contain only ethically sourced, high quality natural ingredients.

We are gaining a lot of media interest in our innovation for menopause Read article on Minerva Reset in The Independent

Minerva Reset has been carefully crafted across 2 years with nutritionists and scientists in the UK, to bring women a long-awaited breakthrough supplement based on 4 different high quality probiotic strains. Our live cultures include Lactobacillus Acidophilus, Bifidobacterium Animalis Lactis, Lactobacillus Rhamnosus and Lactobacillus Plantarum.

What do Minerva Reset's probiotic strains support?

  • Depression

  • Chronic Fatigue Syndrome

  • Lactose intolerance

  • Irritable Bowel Syndrome

  • Yeast infections and UTIs

  • Immune system

  • Periodontal problems

  • Helps regulate neurotransmitters involved in the gut-brain axis.

  • Cholesterol

  • Weight management

  • Insulin resistance

  • Inflammation

  • Strengthens the intestinal lining

  • Skin health

  • Anxiety

  • High blood pressure

  • Cardiovascular health

  • Boosts iron and nutrient absorption

  • Helps reduce oxidative stress

  • Neutralise harmful bacteria in the intestine

  • Improved mood

  • Cognitive and mental health functions

  • Bloating

  • Metabolism

  • Hormonal balance

We know only too well what it's like to have cupboards heaving with different supplements, which is why we purposefully created an all-in-one supplement that also incorporates 16 powerful ingredients to truly pack a punch and further help to kick symptoms into touch. It was so important to us to develop a real solution for our own symptoms (peri and post) and also conduct a trial to accurately assess the supplement's efficacy, which 80 fabulous women took part in, and the results were even more positive than we could have ever hoped for.

Most importantly, we are helping women feel better every day and have built a loyal, happy customer community, thanks to Minerva Reset's unique mix of probiotics with the Ayurvedic nootropic - Bacopa Monnieri, Passionflower, Sage Leaf, soy isoflavones. magnesium, zinc, chromium, vitamins B1, B2, B3, B6, Biotin (B7), Folic Acid (B9), B12, C and D3. This powerful combination of ingredients helps support the following:

  • hormonal balance

  • anxiety

  • bloating

  • metabolism

  • gut health

  • fatigue

  • brain fog

  • hot flushes

  • night sweats

  • low moods

  • sleep

  • low energy

  • dry skin, brittle hair and nails

20 powerful ingredients in one unique formula

The gut-hormone connection is powerful and influences our life in more ways than we ever previously imagined. Even in the wellness and functional medicine worlds we so often see articles about “hormone health” and articles about “gut health” – but not many about the connection between them.

While it may not be the first thing we think about when struggling with hormonal challenges, improving the health of your gut microbiome can be an important part of your journey towards hormone health. I hope this has helped to unlock the gut-hormone ideology behind Minerva Reset and help you discover that truly – it’s all connected.

We'll be covering so much more in our upcoming enews and blogs, so you can hand in your notice as self-confessed meno-health detective and let us take all the hard work out of it for you. There is an abundance of information out there, which is amazing but it can be overwhelming and a little disorientating, so we will try to condense information into an easy-to-read, questions answered type of format.

For further information about our ingredients and what they target, please download information here:

Minerva Wellness - Minerva Reset
Download PDF • 13.42MB

If you would like to try Minerva Reset, please visit our product page below and enter CODE15 at the checkout for a 15% off introductory offer. Valid until

We have been truly surprised by the number of women who approach us whilst taking HRT. Many of them ask us if they can take Minerva Reset in conjunction with HRT, but we are legally unable to answer this as it's a medication. We recommend that you contact your GP first. It's your health, so it's important to check. If you are taking any medication but would like to know if Minerva Reset is compatible, please download our label here and forward to your healthcare practitioner for advice:

Minerva Reset Label Nutritional Information
Download PDF • 775KB

Which symptoms do you struggle with the most?

  • Brain fog

  • Weight gain

  • Hot flushes

  • Hair loss/thinning


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